Searchable abstracts of presentations at key conferences in endocrinology

ea0029p1346 | Pituitary Basic | ICEECE2012

Expression of Ras related proteins in ES cell-derived AVP secreting cells

Kiyota A. , Sugimura Y. , Takagi H. , Fukuoka K. , Nagasaki H. , Oiso Y.

Rab proteins (Rab GTPase) have been implicated in the trafficking and exocytosis of secretary vesicle and play a central role in the secretion of hormones or neurotransmitters. However, the involvement of Rabs and Rab effectors in the regulation of AVP secretion is still unknown. Embryonic stem (ES) cells are pluripotent cells that differentiate into all cell types. Recently, it has been reported that when dissociated ES cells are quickly reaggregeted in low cell-adhesion cult...